Subramaniam Lab
@rasilab.bsky.social
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We study mRNA translation
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Our RNA-linked CRISPR approach is now published! Work led by fantastic graduate student in the lab, Patrick Nugent.
add a skeleton here at some point
4 months ago
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Our RNA-linked CRISPR approach is now published! Work led by fantastic graduate student in the lab, Patrick Nugent.
add a skeleton here at some point
4 months ago
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Excited to share the work of postdoc Rachael Bakker in collaboration with
@lapointelab.bsky.social
! We show that RNA base editors can be repurposed for deep mutational scanning of RNA-RBP interactions at scale both in vitro and in vivo.
www.biorxiv.org/content/10.1...
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Deaminase-based RNA recording enables high throughput mutational profiling of protein-RNA interactions
Protein-RNA interactions govern nearly every aspect of RNA metabolism and are frequently dysregulated in disease. While individual protein residues and RNA nucleotides critical for these interactions ...
https://www.biorxiv.org/content/10.1101/2025.04.11.648485v2
5 months ago
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