Padraic Heneghan
@therealpdogue.bsky.social
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Something of a scientist myself 🔬
Happy to share the final story from my thesis, demonstrating that the common ancestor of all terrestrial fungi had zymocin-like killer plasmids, a toxin system found in some budding yeasts. Come with me on an all-too-familiar, database dumpster-diving journey (1/10)
www.biorxiv.org/content/10.1...
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Zymocin-like killer plasmids were present in the common ancestor of terrestrial fungi
Some budding yeasts secrete killer toxins made by linear dsDNA plasmids located in the cytosol. The best-known example is the Kluyveromyces lactis toxin zymocin, which is encoded by a 9-kb killer plas...
https://www.biorxiv.org/content/10.1101/2025.10.13.682091v1
23 days ago
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reposted by
Padraic Heneghan
Geraldine Butler
3 months ago
New preprint from lab adding to recent interest in yeast centromeres. There are dramatic changes in structure, but location is conserved
www.biorxiv.org/content/10.1...
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Centromeres in budding yeasts are conserved in chromosomal location but not in structure.
The budding yeast Saccharomyces cerevisiae has ‘point’ centromeres, which are much smaller and simpler than centromeres of most other eukaryotes and have a defined DNA sequence. Other yeast taxa have ...
https://www.biorxiv.org/content/10.1101/2025.07.24.666568v1
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Hey! Are you at Beijing
#SMBE
2025? Looking for something to do at 10:20 on Thursday? Come to my talk in Symposium 35 to hear about toxins in Fungi
4 months ago
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