Johan Slotman
@johanslotman.bsky.social
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Super-Resolution Microscopy | Erasmus MC Optical Imaging Centre Rotterdam | www.erasmusoic.nl
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So lets try bluesky as well for science. I'm an assistant professor focusing on advanced fluorescent imaging and image analysis and part of the Erasmus MC Optical Imaging Centre core facility.
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over 1 year ago
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Johan Slotman
Lluis Montoliu
4 days ago
Frank Grosveld, born in 1948, passed away last Friday. He was a colossal scientist in the transcriptional control of gene expression during development and helped us understand the complex regulation of beta-globin genes. His work will remain as a reference. May he rest in peace.
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One of the reasons science was exciting when I was young. Hearing stuff about DNA and the human genome project made me choose to do a laboratory education. RIP mr. Venter.
add a skeleton here at some point
about 2 months ago
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Another great Erasmus MC collaboration by the department of viroscience, psychiatry and the Optical Imaging Centre. This study shows the effects of influenza A virus infection to (iPSC derived) neurons. Great work by the excellent and phd student Feline Benavides
link.springer.com/article/10.1...
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Influenza A virus infection impairs neuronal activity in human iPSC-derived NGN2 neural co-cultures - Acta Neuropathologica Communications
Acta Neuropathologica Communications - Influenza A virus (IAV) infection is associated with a wide variety of neurological complications, of which mild complications like impaired cognitive...
https://link.springer.com/article/10.1186/s40478-026-02292-0
2 months ago
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Johan Slotman
Tom Gauld
2 months ago
My latest cartoon for
@newscientist.com
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Work by Daan te Rietmole, Gerard Jansen,
@bieringslab.bsky.social
@shordijk.bsky.social
, Maurice Swinkels, Petra Bürgisser, Bart Geverts, Joyce Besteboer, Ihor Smal, Thomas Klei, Adriaan Houtsmuller and Frank Leebeek
add a skeleton here at some point
2 months ago
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Nice to share our latest paper with you. In this article we set out to measure the age of platelets in circulation. We related storage age (time in storage) to chronological age.
www.tandfonline.com/doi/full/10....
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Neural network reveals platelet age from fluorescence microscopy images
Platelets are small, anucleate cells with a primary physiological role in vascular damage repair (hemostasis) and initiation of thrombus formation in response to vascular injury. Platelets circulat...
https://www.tandfonline.com/doi/full/10.1080/09537104.2026.2656268?scroll=top&needAccess=true
2 months ago
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Hey Science bluesky. Is there a name for the period between the acceptation email of a paper and when it actually pops up on the website of the journal? 😉
3 months ago
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Johan Slotman
Selçuk Yavuz
7 months ago
Wondering how a fully automated confocal microscopy setup could help biologists with rapid acquisition of quantitative imaging data? Check now our new article published in
#FEBS
Open Bio:
febs.onlinelibrary.wiley.com/doi/10.1002/...
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FEBS Press
RoboMic is an automated confocal microscopy pipeline for high-throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI-driv...
https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70161
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Getting SMART about FRAP enabled us to make many FRAP curves in one imaging session. Now we are doing things like 18 conditions n = 30 in a single overnight session. Study protein dynamics in high throughput. Curious on how? see our publication:
febs.onlinelibrary.wiley.com/doi/full/10....
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FEBS Press
RoboMic is an automated confocal microscopy pipeline for high-throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI-driv...
https://febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70161
7 months ago
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We're having a great Functional Imaging and Super-Resolution Microscopy course this year again. With engaged students learning about FRAP, FRET, STED, FLIM and many more (not necessarily 4 letter) fluorescent microscopy techniques. But also a really nice talk by Ben Giepmans about ColorEM.
8 months ago
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Fun to see a lightsheet image, made at the Erasmus OIC by Lieke Stockman be awarded with the second prize, in the bruker lightsheet image competition.
www.bruker.com/en/products-...
11 months ago
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It's the time of the year (just before holiday) where I can do some random stuff to keep the python muscles warm. Here is a simulation of particles with different movement types in different containers. The bubble like structure was hard to code, but it mostly works.
youtu.be/2YuseN3GGKc
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Particle movement types in different containers
YouTube video by Johan Slotman
https://youtu.be/2YuseN3GGKc
11 months ago
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Sometimes you have to deal with some inevitable truths, like proton beam angle that is fixed. So we flipped a microscope in order to see the effect of proton irradiation on live cells to carefully quantify DNA damage and determine dosage. Read more here:
www.sciencedirect.com/science/arti...
about 1 year ago
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I think it would be pretty interesting to see something in the color olo.
www.nature.com/articles/d41...
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Brand-new colour created by tricking human eyes with laser
The ‘off-the-charts saturated’ greenish hue — called olo — has been seen by only five study participants.
https://www.nature.com/articles/d41586-025-01252-3
about 1 year ago
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So lets try bluesky as well for science. I'm an assistant professor focusing on advanced fluorescent imaging and image analysis and part of the Erasmus MC Optical Imaging Centre core facility.
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over 1 year ago
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