EPIGENETIC HULK
@epigenetichulk.bsky.social
📤 768
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EPIGENETIC HULK SMASH PUNY GENOME. MAKE GENOME GO. LOCATION: NOT CENTROMERE, THAT FOR SURE
NUCLEOSOME NOMENCLATURE JUST FINE! WHY BE SO CRAZY! {[("H3meLIKEY2"])}
www.cell.com/molecular-ce...
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A needed nomenclature for nucleosomes
Keogh et al. propose a nomenclature to clearly and concisely describe the post-translational modifications, proteoforms, and nucleoforms that drive chromatin function. This communicates experimental n...
https://www.cell.com/molecular-cell/abstract/S1097-2765(25)00714-2
about 1 month ago
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🎵WHY DO ENHANCER! SUDDENLY APPEAR! EVERY TIME! THEY ARE NEAR!?! JUST LIKE ME! THEY LONG TO BE! CLOSE TO POLII! 🎵
www.nature.com/articles/s41...
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Distal enhancers loop to proximal enhancers, not to promoters - Nature Reviews Molecular Cell Biology
This Comment posits that enhancers stimulate the transcription machinery only through short-range interactions and, therefore, that enhancer activity at a distance is mediated by chromatin loops betwe...
https://www.nature.com/articles/s41580-025-00889-2
2 months ago
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1992 CALLED THEY WANT THEIR MECHANISM BACK! CHROMATIN REMODELER REMODEL CHROMATIN! SOMETIME THIS GOOD FOR TXN! SOMETIME BLOCK IT! GOOD JOB WITH THE NUCLEOSOMES!
add a skeleton here at some point
2 months ago
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IT BEST HEALTH! FOR SKIN! MAYBE ELAINE FUCHS INVOLVED! NEED CELLULAR EPIGENETICS FOR EVERYTHING PLEASE!
add a skeleton here at some point
2 months ago
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CRAMP! SO ANNOYING BUT NEEDS TO KEEP LINKER HISTONES! EPIGENETIC HULK DO WITHOUT! UNLESS IT THE BAND SO THEN COOL!
www.cell.com/molecular-ce...
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CRAMP1 drives linker histone expression to enable Polycomb repression
Challenging the prevailing view that H1 linker histones represent a general feature of repressed chromatin, Matthews et al. show a specific requirement for H1 in epigenetic repression by PRC2. Ablatio...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(25)00470-8
5 months ago
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www.cell.com/cell/abstrac...
PERTURB EVERYTHING! LOOK AT IT IT! OK GOOD PLAN IF WANT TO KNOW WHAT ONE LITTLE CELL CARES! ALL THESE EVERYTHING STUFF DON'T SMASH REAL BIOLOGY! ONLY PERIPHERAL EASY TO HIT STUFF!
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https://www.cell.com/cell/abstract/S0092-8674(25)00572-0PERTURB
5 months ago
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EPIGENETIC HULK READY TO SMASH AGAIN! GET IN LOSERS!
5 months ago
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