A new CAPRI round is coming up with 4 antibody-antigen targets! The registration opens next Monday (Sept. 22nd). Check it out at www.ebi.ac.uk/pdbe/complex...

Navigating the pre- and post-AlphaFold divide: CAPRI 8th evaluation meeting www.authorea.com/users/348903...

We are happy to announce CAPRI Round 60, with one target: an antibody-peptide complex. Registration is open. Prediction starts June 9th. www.ebi.ac.uk/pdbe/complex...

After a busy CASP/CAPRI year we resume our rolling CAPRI rounds, announcing the 1st target of 2025. It consists of an antibody-glycan complex. The glycan is heptyl α-D-mannopyranoside. Registration for this target is now open. pdbe.org/capri

Early December, the CASP16 Meeting was held in the Palladium resort in Punta Cana, Dominican Republic. Nick Grishin, myself, and Qian Qong presented the assessment of the monomeric structure predictions, the assembly predictions and of monomers in their oligomeric context. 1/n

CAPRI conclusions from the CASP16 assembly session

Improvement in performance with availability of MassiveFold data. Round 58 (CASP stage2 vs stage1)

CAPRI ranking on relative model quality (highlighting predictors that do well on the more difficult targets)

The CAPRI ranking on absolute model quality for CAPRI Round 57 (CASP16 session)

And the main conclusions for this years multimer predictions

How much has the protein assembly modeling field progressed the past two years? At the CASP16 conference in Punta Cana early December we will present the results of the CASP/CAPRI joint blind prediction round: Round 57 (normal), Round 58 (with MassiveFold data) and Scoring (also with MassiveFold)

MassiveFold: unveiling AlphaFold’s hidden potential with optimized and parallelized massive sampling. Out now. www.nature.com/articles/s43...

CASP16 / CAPRI Round 57 has started. The first target was released today.

Impact of AlphaFold on structure prediction of protein complexes: The CASP15-CAPRI experiment doi.org/10.1002/prot...

Welcome to the bluesky presence of the community-wide CAPRI protein docking and assembly modeling experiment. Please note the 8th CAPRI assessment meeting will be held Feb 12-16 in Grenoble, France, back-to-back with the Integrative Computational Biology meeting. Details to follow.