The rules of immunity are different in early life! Lead author Dr. Yue Xing finds that early life DCs sense allergens and trigger inflammation directly in skin. This in-situ activation state emerges from a developing HPA and low glucocorticoids. #Naiklab @nature.com www.nature.com/articles/s41...

Excited to share our lab’s latest preprint: In vivo single-cell CRISPR screening for microproteins identifies a critical ribosomal component. Check out how we systematically explore #microprotein functions and how they expand the cellular proteome!

Our new preprint is out on @biorxivpreprint! 🔗 www.biorxiv.org/content/10.1... This work done as part of my PhD at @lableibundgut.bsky.social We show that the commensal fungus Malassezia promotes skin barrier function via AhR signaling, through secreted tryptophan-derived indoles.

"Ultimately, these changes lead to insufficient activation of a pathway controlled by the aryl hydrocarbon receptor (AHR)" not to be that smug guy on the Internet but this is why I keep yelling about AhR and Regulatory T cells and immune conditions liminalnest.wordpress.com/2024/05/28/b...

Our first 🦋 post! Very happy to share our latest paper just out in Cell Reports, exploring the crosstalk between immune and epithelial cells in the gut. Check it out! @vivianlilab.bsky.social @kingscollegelondon.bsky.social www.cell.com/cell-reports...

Check out our latest work on cutaneous immunity against Malassezia. Just out in Mucosal Immunology. Congrats to Meret Tuor and colleagues. Thanks to Mark Stappers, Neil Gow and Selinda Orr for your contributions. www.sciencedirect.com/science/arti...