Ben Wielockx (@wielockx.bsky.social)

Our latest preprint shows what prolonged glucocorticoid exposure can do to the immune system: HIF1⬇️🐁->GC⬆️(+Receptor)-HSPC->Immune❄️☀️ www.biorxiv.org/content/10.1... CRC-TRR 205 @adrenal-research.bsky.social ! #hypoxia #glucocorticoids #HIF #HSC #Immunology

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Hypoxia Inducible Factor 1α-driven steroidogenesis impacts systemic hematopoiesis Glucocorticoids regulate hematopoiesis, but how chronic elevation of endogenous glucocorticoid production affects hematopoietic stem cell (HSC) function and immune cell development remains incompletel... https://www.biorxiv.org/content/10.1101/2025.03.20.644292v1