Need support for your protein degrader projects? Join our webinar for insights into our gene-to-structure workflow for producing high-quality, structure-grade CRBN-DDB1 ready for structure determination. Register: nimgs.zoom.us/webinar/regi...

🧪 Just two days away! Join us for a gene-to-structure case study, from protein production to a 3.1 Å structure for CYP3A4, a 57 kDa cytochrome P450 monooxygenase and ask your questions live. BONUS: Sign up for the webinar to get early access to the whitepaper! nimgs.zoom.us/webinar/regi...

🧪 Conflicting results from DLS? #CryoTEM imaging can provide quantitative and qualitative data for smaller particles, like iron nanoparticle formulations, all in one study. Reach out to [email protected] to learn how cryo-TEM imaging can help you meet milestones faster.

🧪 Running into roadblocks with your proteins? Join us for a guide to setting your structure determination project up for success and case study of CYP3A4, a 57 kDa cytochrome P450 monooxygenase solved to 3.1 Å. P.S. Get early access to the case study by registering!

🚀 Fast track your #HPV therapeutics with #cryoTEM imaging. From initial characterization to 3D structures, we support you throughout the entire pipeline, including regulatory submissions. 🧪 Want the proof? See our published work on Gardasil®: www.nanoimagingservices.com/resources/ho...

🧪 Skip the trial and error for structure determination of soluble proteins. Join the #webinar 10/8 for a gene-to-structure case study of CYP3A4, a 57 kDa cytochrome P450 monooxygenase, solved to 3.1 Å by #cryoEM. nimgs.zoom.us/webinar/regi...

🧪 Are you using cryo-EM to look at small soluble proteins? Walk through each stage from protein production to structure determination, with practical insights and lessons from a recent case study on CYP3A4 with live Q&A. Register: nimgs.zoom.us/webinar/regi...

When it comes to #lentivirus characterization, seeing is believing. Traditional analytical methods tell you what's there, but #cryoTEM shows you exactly how it's organized. Learn more: www.nanoimagingservices.com/nanoparticle...

How do you choose a nanoparticle characterization method? While there are many techniques available, cryo-TEM stands out by revealing information other methods miss. Dive into the comparison: www.nanoimagingservices.com/about/blog/v...

Ever wondered how buffers impact #cryoEM structures? 🧪 DMSO and cryoprotectants can be tolerated at low concentrations. If you're curious if your buffer will be compatible, schedule a call with our experts: www.nanoimagingservices.com/contact

Are you looking for comprehensive, reliable particle sizing analysis? From LNPs to iron nanoparticles, cryo-TEM semi-automated particle contouring and sizing provides precise particle size distribution measurement for a range of samples. Learn more at www.nanoimagingservices.com/nanoparticle...

🧪 Ever wondered what the difference is between #cryoEM and #negativestain #TEM is? Find out in today's FAQ Friday!

Do you know how #LNPs show up in #cryoTEM versus negative stain TEM? Want to learn more about the advantages of cryo-TEM for LNPs and other #liposomal samples? Tune in for the full webinar from Dr. Maria (Mandy) Janssen:

During a recent webinar, we were asked, “How does automated cryo-TEM particle picking for AAV full/empty capsids compare to other orthogonal methods?” Watch the webinar in full for a great explanation of cryo-TEM imaging & analysis of AAV, and more of your great questions: youtu.be/w7kRfNZX_SI

Poor contrast TEM images got you feeling grey? No problem! Our latest tutorial will help you quickly & easily enhance the contrast and add scale bars to your #cryoTEM or negative stain TEM images so they’re ready for publication: www.nanoimagingservices.com/about/blog/e...

Did you miss our webinar last week? You can now catch this amazing talk from Dr. Mandy Janssen about #cryoTEM #LNP characterization, NIS’s proprietary AI tools for image analysis, and a case study showing unique insights only cryo-TEM can provide. Catch it here:

Are you struggling to solve the structure of your #RNA molecule? Cryo-EM study RNA in its native, unbound state, without the influence of associated proteins? Learn more about the potential of #cryoEM single particle analysis for protein-free RNA: www.nanoimagingservices.com/about/blog/u...

Unexpected results in your #LNP formulations? Join our webinar + Q&A to learn how #cryoTEM imaging can help provide answers. We will reveal how cryo-TEM can provide reliable, reproducible data (size, morphology, lamellarity, blebs) in one dataset. Sign up: nimgs.zoom.us/webinar/regi...

Have you signed up yet? In just 1 week, Dr. Mandy Janssen will be giving a webinar + Q&A diving into the applications of #cryoTEM for #LNP development! Don't miss out on this deep dive: nimgs.zoom.us/webinar/regi... Can't make it live? Sign up to get a recording, or send in your questions!

FAQ Friday! Dr. Sarah Strassler Sulley touches on the differences between cryo-EM and HDX for epitop emapping. Want more? Check out our blog with an in-depth technique comparison: www.nanoimagingservices.com/about/blog/e...

Looking for ways to enhance your #LNP analysis tools? Dr. Mandy Janssen will present how #cryoTEM imaging & automated analysis can reveal multiple CQAs all in one dataset. Questions? Stick around after the webinar for a Q&A with Mandy. Sign up: nimgs.zoom.us/webinar/regi...

How big are cryo-EM grids exactly? Find out!

It's tomorrow! Join us to learn about automated cryo-TEM analysis of AAV full/empty capsid ratios. Can't make it? Sign up anyway to receive a recording. Don't miss this webinar + Q&A session: nimgs.zoom.us/webinar/regi...

Webinar! Enhance LNP Development: Cryo-TEM & Automated Image Analysis Tools Enable high-resolution visualization of LNPs in near-native state, analyze multiple CQAs in 1 dataset, & use automated image analysis tools for quantitative measurements. Register: nimgs.zoom.us/webinar/regi...

One week out! Join us for a webinar, "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios". Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions. Sign up: nimgs.zoom.us/webinar/regi...

Don't miss this webinar! "Automated Cryo-TEM Analysis of AAV Empty/Full Capsid Ratios" on 5/15, 11am PST, 2pm EST. Whether you're troubleshooting or aiming to streamline AAV manufacturing process, we'll demonstrate how cryo-TEM can drive faster informed decisions. nimgs.zoom.us/webinar/regi...

Live webinar! Learn about automated AAV empty/full capsid ratio analysis with cryo-TEM on Thursday May 15, 11am PST, 2pm EST. Learn the advantages of cryoTEM for assessing AAV formulations & how AAV empty/full capsid status is determined. Sign up: nimgs.zoom.us/webinar/regi...

What are sample size requirements for Single Particle Analysis cryo-EM? Join Dr. Sarah Strassler Sulley to find out! Questions about cryo-EM? Let us know!

Did you know cryo-TEM is the only technique that can visualize blebbing on LNPs? Check out our latest blog for detailed examples of blebs & bilayers, and a literature review: bit.ly/42oxkWH Email us at [email protected] to get started imaging your lipid nanoparticles!

It’s FAQ Friday! A well characterized sample can make all the difference for cryo-EM structure determination. What characterization techniques do we recommend? Check in with Dr. Sarah Strassler Sulley to find out! What else do you want to know about cryo-EM? Let us know.

The third and final chapter of our webinar series “Cryo-EM: Back to Basics” is on demand. Hear from Giovanna about challenges in #cryoEM, how to overcome them. Catch all three chapters: Chapter 1: youtu.be/e8GyDe4_BAQ Chapter 2: youtu.be/2dBnPVkaoFs Chapter 3: youtu.be/kUGNSTGc8II

FAQ Friday! Have you ever wondered about the difference between Krios & Glacios microscopes? Find out now! What #cryoEM questions do you have?

Blebs on LNPs are mysterious & strange. Where do they come from? What impact do they have? Scientist Brent Wood explores blebs & other morphological features of LNPs that can only be visualized with cryo-TEM. Check out the images & literature review: www.nanoimagingservices.com/about/blog/t...

Seeing unexpected results in your gene & drug delivery vehicles? Cryo-TEM imaging & analysis can help. Automated, quantitative payload encapsulation analysis can accelerate your therapeutic pipeline and help inform efficacy and safety. www.nanoimagingservices.com/nanoparticle...

Don't miss the last session of the webinar series "Cryo-EM: Back to Basics" to hear CSO Giovanna Scapin's perspective on overcoming obstacles in cryo-EM structure determination. Chapter 3: Overcoming Limitations | Tuesday, March 25, 11am PST, 2pm EST Register: nimgs.zoom.us/webinar/regi...

Cryo Electron Tomography can reveal the 3D structures of heterogeneous nanoparticles, such as liposomes, LNPs, exosomes, extracellular vesicles. 3D volumes can provide a complete picture of morphology, surface decorations, & internal composition. Learn more: bit.ly/cryo-et

Accelerate your discovery pipeline with a streamlined gene-to-structure workflow. Customized services include protein production (mammalian, bacterial, insect), antibody production & sryo-EM structure. Explore our new offerings: www.nanoimagingservices.com/structural-b...

Is your protein failing to crystallize? Cryo-EM can overcome bottlenecks and sample limitations associated with XRC. Compare cryo-EM & crystallography side-by-side: www.linkedin.com/smart-links/...

Did you make our cryo-EM webinar last week? Dive into pre-processing, how to interpret 2D classes, 3D reconstructions from the initial map to final structure with CSO Giovanna Scapin. Catch it here: youtu.be/2dBnPVkaoFs Sign up for Overcoming Limitations, on 3/25: nimgs.zoom.us/webinar/regi...

Phase appropriate cryo-TEM imaging can provide quantitative assessment of CQA's including particle sizing (whole particles & dense cores), aggregation, morphology analysis, and uniformity in order to show comparability of biosimilars or generics, stability, & more. Learn more: bit.ly/ironnp

Dive into cryo-EM data processing & interpretation during chapter 2 of our three-part series led by CSO Giovanna Scapin! Whether you're new to cryo-EM or want to improve your knowledge, this webinar with live Q&A series is perfect for the cryo-curious. Register:

Discover #cryoTEM images of your lipid nanoparticles, drug-loaded liposomes, & micelles. Gain critical insights into morphology, blebbing, payload, & more. Email us at [email protected] to learn more.

Struggling with protein quality for cryo-EM? We've acquired Proteos, a US-based CRO, to offer expert protein production services. Experience seamless gene-to-structure supported by exceptional recombinant protein expression, antibody production, & protein purification: bit.ly/40unjaJ

Comprehensive analysis of the effects of storage conditions (buffer, pH, temperature, time) on LNPs & liposome morphology is crucial for maintaining stability. Cryo-TEM stability studies can be done at any phase, & method validated can be used for regulatory filings. Learn more: bit.ly/41oQFYJ

The quality of cryo-EM data hinges on the intricate details of cryo-grid preparation. Grid materials, air-water interface and vitrification process all impact sample behavior. Mastering these is essential to overcoming challenges and unlocking cryo-EM. Dive into the blog: bit.ly/cryo-grid

Do you know what unique insights cryo-TEM imaging can provide about LNP CQAs? In a joint study with Phosphorex, we show how cryo-TEM reveals effects of process changes like time, buffer, & temp on morphology, like blebs, that other analytical methods can’t capture: www.linkedin.com/smart-links/...

#Webinar series "Cryo-EM: Back to Basics" starts tomorrow! CSO Giovanna Scapin will walk you through the process of #cryoEM from start to finish over this three part series. Bad time? No worries! Register & we'll send you a recording after: nimgs.zoom.us/webinar/regi...

Join Dr. Brent Wood & Dr. Sarah Dunn for the WCBP Symposium this week in Washington D.C. Drop by booth 15 to discuss how GMP compliant cryo-TEM, negative stain TEM, and method validation services can support your regulatory filings.

The three-part webinar series "Cryo-EM: Back to Basics" starts next Thursday! Whether you're new to cryo-EM or want a refresh, this series will have something for you. Then, ask CSO Giovanna Scapin your questions & get answers in real time. Register now: nimgs.zoom.us/webinar/regi...

From pre-clinical studies to commercial product, we're the trusted partner in phase-appropriate characterization of nanoparticle formulations! Cryo-TEM imaging unlocks CQAs for viral, lipid, protein, & inorganic formulations, like morphology, size, encapsulation. Learn more https://bit.ly/4j54zGe