🔥 Most-Read in 2025 (so far): From chemovar classification and THC/CBD pharmacology to clinical and product studies — here are the Top 10 most-requested papers from Cannabis and Cannabinoid Research! 🌿 📖 home.liebertpub.com/publications...

🌿 Cannabis and Cannabinoid Research celebrates 10 years by highlighting the Top 10 most-downloaded articles of all time! From opioid substitution to CBD safety, immune function, and pain management—these papers shaped a decade of cannabis science. 📖 Explore more: home.liebertpub.com/publications...

🎉 Cannabis and Cannabinoid Research turns 10! We’re celebrating by featuring the most-downloaded studies from the past decade and from 2025—research that’s shaped how we understand cannabis, cannabinoids, and health. Stay tuned for our highlights! #CannabisResearch #Cannabinoids #10YearsOfCCR

🌿 Study: Among adults with cannabis use disorder, 89% used ≥1 other substance, 34% used 2+. Mood & personality disorders were linked to higher polysubstance use. Screening recommended. Read more: doi.org/10.1177/2578... #CannabisResearch #CUD #PolysubstanceUse #MentalHealth

💚 Study: In adults without preexisting CKD, regular cannabis use was not linked to higher risk of chronic kidney disease, rapid kidney decline, or albuminuria. Read more: doi.org/10.1177/2578... #CannabisResearch #KidneyHealth #LongitudinalStudy

🌿 Study: Cannabis purchasing decisions vary by user type. Retail employees care less about THC, more about brand & appearance. Frequent users value strain, production method, price & appearance. Read more: doi.org/10.1177/2578... #CannabisResearch #ConsumerBehavior #THC #CannabisPolicy

🚦 Study: Recreational cannabis legalization & dispensary openings in CT did not significantly change motor vehicle accident rates. Read more: doi.org/10.1177/2578... #CannabisResearch #RoadSafety #CannabisLegalization

🌿 Cannabis affects the brain differently across the lifespan: -In utero & teens: High neurodevelopmental risk -Late adulthood: Rising use, low perceived risk -Policy, education, & research needed to reduce harm. Read more: doi.org/10.1177/2578... #CannabisResearch #THC #BrainHealth #Neurodevelopment

🌿 Pilot trial: Oral CBD ± THC reduced specific eCBome mediators (2-EPG & 2-OG) in people with HIV on ART. No major gut microbiome changes observed. Larger studies needed. Read more: doi.org/10.1177/2578... #CannabisResearch #CBD #THC #HIV #EndocannabinoidSystem #GutMicrobiome

🌿 New study: PEG carrier oil ↑ plasma THC vs PG/VG. Adolescents less sensitive to locomotor suppression, females metabolize THC slower. High-dose vaporized cannabis → hypothermia & antinociception in mice. Read more: doi.org/10.1177/2578... #CannabisResearch #THC #VaporizedCannabis #Neuroscience

🌿 New review: Pure CBD may help social & generalized anxiety; Δ9-THC may reduce PTSD nightmares & tics in Tourette syndrome. Mixed formulations show no clear effect. More high-quality trials needed. Read more: doi.org/10.1177/2578... #CannabisResearch #CBD #THC #Anxiety #Tourette

🧪 Study published in Cannabis and Cannabinoid Resarch finds Cannabigerol (CBG) safe and non-toxic in animal models, with lifespan extension benefits in worms. Supports CBG’s potential as a safe therapeutic compound. www.liebertpub.com/doi/10.1089/...

🧠 Study published in Cannabis and Cannabinoid Research suggests THCV may improve sustained attention and is well tolerated in healthy adults. Promising early evidence for therapeutic uses in attention disorders. www.liebertpub.com/doi/10.1089/...

📈 Cannabis use is up among older adults, raising health concerns. Age matters in cannabis effects—new study highlights need for targeted public health efforts. More here:https://www.liebertpub.com/doi/10.1177/25785125251361926

🔬 Study: Δ10-THC Isomers A 2023 study in Cannabis and Cannabinoid Research shows both cis- and trans-Δ10-THC act as CB1 receptor antagonists, offering new insight into cannabinoid pharmacology and potential therapies. 👉 www.liebertpub.com/doi/10.1089/...

📢 New meta-analysis: 1 in 3 pediatric patients on therapeutic cannabinoids experience GI side effects, with higher rates in interventional studies (47%). Important for clinicians & families to consider! 🩺 🌿https://www.liebertpub.com/doi/10.1089/can.2024.0104 #Cannabinoids

** New study Most adults with cannabis use disorder also struggle with additional substance use disorders—alcohol, opioids, stimulants, sedatives—highlighting the need for broader treatment approaches. 🔗 Read the full study: www.liebertpub.com/doi/10.1177/... #PolysubstanceUse #CUD #MentalHealth

🌱 New Study: Regular cannabis use not linked to higher risk of CKD or kidney decline in adults tracked over several years. No adverse kidney effects found in adjusted analyses. 🔗 Read the full study: doi.org/10.1177/2578... #CannabisResearch #KidneyHealth

🚗🌿 New study: Connecticut’s recreational cannabis legalization (Jan 2023) did not increase motor vehicle accidents — statewide or near dispensaries. Evidence-based insight for cannabis policy debates. 🔗 doi.org/10.1177/2578... #CannabisResearch #RoadSafety #CannabisPolicy #THC #PublicHealth

🚨 Save the Date! 🚨 The MACRC 2025 Conference — the first official ICRS Chapter meeting 🍃 📅 Nov 14–16, 2025 | 📍 Kitty Hawk, NC Abstracts & registration open (early bird thru Sept 21)! 👉 www.m-acrc.org #CannabinoidResearch #MACRC2025 #ICRS

🔎 2023 research shows Δ10-THC isomers bind CB1 receptors but don’t activate them — acting as antagonists, unlike psychoactive Δ9-THC. Full study: doi.org/10.1089/can.... #Delta10THC #CannabisScience #THC #CB1Receptor

🌿 Check out the 2023 Special Issue on Cannabidiol (CBD) in CCR! This issue covers CBD’s potential for insomnia, stress, chronic pain, immune modulation, brain health, & more — featuring reviews, original research, and clinical trials. www.liebertpub.com/doi/full/10....

Pilot study finds oral cannabis for taxane-induced neuropathy is safe but may worsen some symptoms vs. placebo. More research needed to clarify its role in cancer care. Read more: doi.org/10.1089/can.... #TIPN #Cannabis #CancerPain #ClinicalResearch

New study shows CBD—but not THC—increases anti-inflammatory lipid mediators in humans, highlighting CBD’s potential for treating inflammatory diseases. Read more: doi.org/10.1089/can.... #CBD #THC #Inflammation #CannabisResearch

New review finds prenatal cannabis exposure linked to lower birth weight and potentially worse infant health at delivery. More research is needed as cannabis use rises. Use caution during pregnancy! Read more: doi.org/10.1089/can.... #Cannabis #Pregnancy #BirthOutcomes #THC

🧠 New zebrafish study 🐟 shows that CBD pretreatment can reduce seizures ⚡ and protect against glutamate uptake issues in status epilepticus. Neuroprotective promise! 🌿 Read: www.liebertpub.com/doi/10.1089/...

🍳 Cooking methods impact cannabis 🌿 and kratom 🍃 compounds. Boiling/steaming retain the most THC 🔥; mitragynine in kratom decreases with heat. Important for home-prepared products. www.liebertpub.com/doi/10.1089/...

🚨 CBD Gummy Study: Accuracy Issues & Hidden THC A new study found 70% of CBD gummies had inaccurate CBD doses, & nearly 40% contained THC—often without consumer knowledge. ⚠️ Urgent need for stronger regulation and quality control in the CBD market. 🔗 www.liebertpub.com/doi/10.1089/...

🧪 New Study: Combining CBD with low-dose buprenorphine enhances pain relief and reduces the risk of respiratory depression—a key opioid danger. 💡 A promising step toward safer pain management strategies. 🔗 www.liebertpub.com/doi/10.1089/... #OpioidSafety #CBD #Pain

🌿 37% of California Adults Use Cannabis Most use it at home, get it from licensed dispensaries, and report mental and physical benefits. But—despite feeling comfortable talking to doctors—most rely on the internet or friends/family for information. 📖 www.liebertpub.com/doi/10.1089/...

🇯🇵 Japan’s 2023 Cannabis Reform: For the first time since 1948, Japan has amended its Cannabis Control Act—allowing medical use and industrial hemp while keeping strict THC limits and criminal penalties. Major shift, cautious modernization. 🔗 doi.org/10.1089/can....

⚠️ New Study: 67% of CBD tinctures sold in the U.S. were inaccurately labeled—many had significantly different CBD levels than listed. Some even contained THC without disclosing it. 📢 Highlights the urgent need for stronger regulation and consumer protections. 🔗 www.liebertpub.com/doi/10.1089/...

New study analyzed 🍬 cannabis edible brand names & found THC brands often use food & culture themes, while CBD brands lean health & wellness. Names may shape consumer appeal & risk perceptions. Read more: doi.org/10.1089/can.... #CannabisResearch #THC #CBD

📢 New in Cannabis & Cannabinoid Research: Haney et al. tested daily oral cannabis (300mg CBD:15mg THC) vs placebo for taxane-induced neuropathic pain. 🟢 Well-being improved 🔴 Cannabis worsened several outcomes vs placebo 📄 www.liebertpub.com/doi/abs/10.1... @meghaney.bsky.social

New study shows CBD boosts anti-inflammatory lipid mediators in humans, but THC does not. Supports CBD’s potential in treating inflammatory diseases. Read more: doi.org/10.1089/can.... #CannabisResearch #CBD #Inflammation

Recent study: Local CBD 🌿 reduces pain in Complex Regional Pain Syndrome Type I (CRPS-I) in mice 🦵🔥 via CB1 & TRPM8 targets. Promising for neuropathic pain treatment! doi.org/10.1089/can.... #CRPS #CBD #PainRelief #Cannabinoids

Study shows cannabinoid receptor 2 (CB2R) knockout mice have altered hippocampal function: increased synaptic transmission, reduced plasticity, & impaired network synchrony. Insights into CB2R’s role in brain function & potential neuropsychiatric impacts. doi.org/10.1089/can....

🚨 Researchers! Access FREE brain & organ tissues from adolescent THC-exposed rodents via the ICAL Tissue Bank @ UCI. No DEA license needed. Great for pilot data & grant apps. Apply now—brain tissues go fast! 📦 cannabis.uci.edu/ical/tissueb... #CannabisResearch #THC

Study shows cannabinoid receptor 2 (CB2R) knockout mice have altered hippocampal function: increased synaptic transmission, reduced plasticity, & impaired network synchrony. Insights into CB2R’s role in brain function & potential neuropsychiatric impacts. doi.org/10.1089/can....

🔥 Study finds that cannabis smoke isn’t uniform—cannabinoid and terpene delivery changes as you smoke. Early puffs = more terpenes Later puffs = more cannabinoids ➡️ Inhaled content shifts with each puff. 📖 Study #CannabisResearch #THC #Terpenes #InhalationScience

🚀 New study tests NanoCelle®, a nanoparticle 1:1 THC:CBD spray, in advanced cancer patients. 🧬 Orobuccal delivery = bypasses liver 📈 ~2x ↑ bioavailability vs sprays THC: ~27% CBD: ~10% Big step for cannabinoid delivery tech in cancer care. 📖 doi.org/10.1089/can....

Is the cannabis ""entourage effect"" fact or hype? 🌿 A 2024 review finds limited evidence supporting it as a stable, predictable phenomenon—more research needed before clinical claims. 🔗 doi.org/10.1089/can.... #CannabisResearch #EntourageEffect

Chronic low-dose cannabinoids show mixed effects in an Alzheimer’s mouse model 🧠: -THC alone caused anxiety & depression-like behavior -CBD+THC combo improved spatial memory All cannabinoids increased insoluble beta-amyloid 1-42 in cortex More research! doi.org/10.1089/can.... #Alzheimers #CBD #THC

🐟💥 New study: CBD pretreatment reduces seizures in zebrafish exposed to kainic acid. 🧠 ↓ Seizure intensity ⏱️ ↑ Time to status epilepticus ⚡ CBD may protect against excitatory brain disruption More: doi.org/10.1089/can.... #CBD #EpilepsyResearch #ZebrafishModel #Cannabis

Study in Cannabis & Cannabinoid Research: Regular cannabis use in Spain shows no major public health impact, but links to sleep issues & possible dependence. ~30% reduced prescription meds. Social support, not cannabis, predicted well-being. 🔗 doi.org/10.1089/can.... #Cannabis

🍃🔥 New study shows how cooking affects cannabis & kratom compounds. 🫖 Boiling/steaming = more THC retained ⚗️ Kratom’s mitragynine drops 20–50% 📉 Phenolic content drops in all methods Details: doi.org/10.1089/can.... #CannabisResearch #Kratom #THC #CBD #Edibles

🧪 What’s in your CBD? Study of 80 products found variable minor cannabinoids: ✅ CBDV (100%), CBG (77%), CBC (72%), CBN (67%) ❌ No Δ8-THC ⚠️ Most unlabeled 📊 Consumers may not know what they’re taking 🔗 doi.org/10.1089/can....

New meta-analysis: 1 in 3 kids on therapeutic cannabinoids experience GI side effects—especially in interventional studies. Dravet syndrome patients may be most at risk. Crucial data for risk-benefit talks in pediatrics. 🔗 doi.org/10.1089/can.... #CannabisResearch #Pediatrics

During COVID, many adults with chronic health conditions turned to cannabis to manage symptoms — most without a medical recommendation. 🧠 Mental health, 💤 sleep, and 💢 pain were the top concerns. Highlights the need for more research! 🔗 doi.org/10.1089/can....

Small pilot study tests THC+CBD oil for teens with Tourette’s. ✔️ Feasible and well-tolerated ✔️ Some saw symptom improvement Next step: larger trials to test effectiveness. 🔗 doi.org/10.1089/can.... #TouretteSyndrome #CannabisResearch #Pediatrics #THC #CBD