Hydration Network Drives Activation and G Protein Selectivity in GPR174 www.biorxiv.org/content/10.1101/2025.10.06.680656v1 #cryoem

Freeze-denaturation mitigation in surimi by Naematelia aurantialba polysaccharides: structural stabilization and ice recrystallization inhibition pubmed.ncbi.nlm.nih.gov/41046892/ #cryoem

Gastrointestinal distribution of engineered biodegradable urease-powered nanomotors pubmed.ncbi.nlm.nih.gov/41046940/ #cryoem

Structure of the Gq-coupled adhesion receptor ADGRL4, a GPCR implicated in cancer www.biorxiv.org/content/10.1101/2025.10.03.680274v1 #cryoem

Cryo-EM studies of amyloid-β fibrils from human and murine brains carrying the Uppsala APP mutation (Δ690-695) pubmed.ncbi.nlm.nih.gov/41044681/ #cryoem

Structural basis for DCAF2 as a novel E3 ligase for PROTAC-mediated targeted protein degradation pubmed.ncbi.nlm.nih.gov/41045927/ #cryoem

Unveiling the unique interaction mechanism of herpes simplex virus 2 glycoprotein C with C3b www.biorxiv.org/content/10.1101/2025.10.04.680448v1 #cryoem

Structural and mechanistic insights into translation initiation on the enterovirus Type 1 IRES www.biorxiv.org/content/10.1101/2025.10.04.680434v1 #cryoem

Thick filament molecular interfaces play a critical role in pathogenesis of hypertrophic and dilated cardiomyopathy www.biorxiv.org/content/10.1101/2025.10.03.680256v1 #cryoem

Helical Reconstruction of Amyloids in cryoSPARC www.biorxiv.org/content/10.1101/2025.10.03.680389v1 #cryoem

Cryo-EM structure of the FtsH periplasmic domain reveals functional dynamics www.biorxiv.org/content/10.1101/2025.10.03.679995v1 #cryoem

Translation landscape of stress granules pubmed.ncbi.nlm.nih.gov/41042876/ #cryoem

Structural mechanism of mRNA decoding by mammalian GTPase GTPBP1 pubmed.ncbi.nlm.nih.gov/41040188/ #cryoem

HIV Env trimers elicit NHP apex cross-neutralizing antibodies mimicking human bNAbs pubmed.ncbi.nlm.nih.gov/41040226/ #cryoem

Prediction of TdP Arrhythmia Risk Through Molecular Simulations of Conformation-specific Drug Interactions with the hERG K + , Na V 1.5, and Ca V 1.2 Channels pubmed.ncbi.nlm.nih.gov/41040275/ #cryoem

Human SerRS/SIRT2 complex structure reveals cross regulation between translation and NAD + metabolism pubmed.ncbi.nlm.nih.gov/41040366/ #cryoem

The CAGE complex: a hollow, megadalton, protein assembly in prokaryotic and eukaryotic microbes pubmed.ncbi.nlm.nih.gov/41040395/ #cryoem

Structural basis for regulation of Frizzled-4 signaling by the co-receptor Tetraspanin-12 pubmed.ncbi.nlm.nih.gov/41040411/ #cryoem

Validation of 3D cryoEM single-particle reconstruction correctness and handedness with Ewald's sphere correction pubmed.ncbi.nlm.nih.gov/41041115/ #cryoem

Overcoming air-water interface-induced artifacts in Cryo-EM with protein nanocrates pubmed.ncbi.nlm.nih.gov/41041536/ #cryoem

Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail pubmed.ncbi.nlm.nih.gov/41042861/ #cryoem

A triple take on antigen receptor recognition of PE pubmed.ncbi.nlm.nih.gov/41043395/ #cryoem

The mechanism of thioamide formation by the YcfA-YcfC system in 6-thioguanine biosynthesis pubmed.ncbi.nlm.nih.gov/41044055/ #cryoem

A physiologically-relevant intermediate state structure of a voltage-gated potassium channel pubmed.ncbi.nlm.nih.gov/41044058/ #cryoem

Template Learning: Deep learning with domain randomization for particle picking in cryo-electron tomography pubmed.ncbi.nlm.nih.gov/41044063/ #cryoem

Molecular insights into how the motions of the β-barrel and POTRA domains of BamA are coupled for efficient function pubmed.ncbi.nlm.nih.gov/41044071/ #cryoem

Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms pubmed.ncbi.nlm.nih.gov/41044083/ #cryoem

Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation pubmed.ncbi.nlm.nih.gov/41044155/ #cryoem

CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy pubmed.ncbi.nlm.nih.gov/41044311/ #cryoem

Mechanistic insights into Cas13d enzymes from cryo-EM structures of CasRx and DjCas13d pubmed.ncbi.nlm.nih.gov/41036620/ #cryoem

A multi-dentate, cooperative interaction between endo- and exo-ribonucleases within the bacterial RNA degradosome pubmed.ncbi.nlm.nih.gov/41036625/ #cryoem

Amyloid Fibrillation of a Ninjurin-1-Derived α-Helical Peptide: Structural Insights into Conformational Transition pubmed.ncbi.nlm.nih.gov/41037056/ #cryoem

Challenges and opportunities in technologies and methods for lncRNA structure determination pubmed.ncbi.nlm.nih.gov/41039493/ #cryoem

Absolute hand determination of glycofibrils from natural sources in cryo-EM www.biorxiv.org/content/10.1101/2025.09.30.679555v1 #cryoem

Few-Shot Classification of Cryo-EM Micrographs Using Triplet Loss Embeddings www.biorxiv.org/content/10.1101/2025.10.01.679860v1 #cryoem

KNexPHENIX: A PHENIX-Based Workflow for Improving Cryo-EM and Crystallographic Structural Models www.biorxiv.org/content/10.1101/2025.10.02.680106v1 #cryoem

Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota pubmed.ncbi.nlm.nih.gov/41034344/ #cryoem

A Simple Modification of a Commercial Plunge-Freezer to Allow Time-Resolved Vitrification for Cryo-EM Analyses of Light-Activated Proteins pubmed.ncbi.nlm.nih.gov/41028346/ #cryoem

Structures of Myxobacterial Phytochrome Revealed by Cryo-EM pubmed.ncbi.nlm.nih.gov/41028347/ #cryoem

Hydrogen-Deuterium Exchange Coupled to Mass Spectrometry-Based Analysis of Phytochrome Photoreceptors pubmed.ncbi.nlm.nih.gov/41028348/ #cryoem

Distance-AF improves predicted protein structure models by AlphaFold2 with user-specified distance constraints pubmed.ncbi.nlm.nih.gov/41028845/ #cryoem

Comparative structural analysis of IS21 transposition complexes using Cryo-EM and AlphaFold3 pubmed.ncbi.nlm.nih.gov/41029432/ #cryoem

Tool antibody fragments reveal multiple conformations of the rhodopsin-Gi signaling complex pubmed.ncbi.nlm.nih.gov/41029899/ #cryoem

High-Affinity, Structure-Validated and Selective Macrocyclic Peptide Tools for Chemical Biology Studies of Huntingtin pubmed.ncbi.nlm.nih.gov/41030958/ #cryoem

Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter pubmed.ncbi.nlm.nih.gov/41031034/ #cryoem

Molecular architecture for state transition: insights from structural biology and evolutionary trajectories pubmed.ncbi.nlm.nih.gov/41031733/ #cryoem

Transcriptional reprogramming by bacteriophage T4: turning the host transcriptional machinery to the dark side pubmed.ncbi.nlm.nih.gov/41031825/ #cryoem

S-nitrosoglutathione reductase as a therapeutic target for diabetic vascular complications in rodent models pubmed.ncbi.nlm.nih.gov/41032622/ #cryoem

Structural insights into Wnt/β-catenin signaling regulation by LGR4, R-spondin, and ZNRF3 pubmed.ncbi.nlm.nih.gov/41034211/ #cryoem

The slit diaphragm in Drosophila exhibits a bilayered, fishnet architecture pubmed.ncbi.nlm.nih.gov/41034222/ #cryoem