BBI's annual Long-Read Sequencing Symposium is set for Sept. 16th, 10 am to 4:30 pm; poster session - 11:45 to 12:50. Location is UW's Foege Hall South, 3720 15th Ave NE, Seattle. Visit Redcap for details/registration; registration ends Sept. 5 at 12 noon. redcap.iths.org/surveys/?s=8...

We’ve got two exciting VESS speakers lined up for July 1 🤩 🎙️Daniel Zimmerman postdoc @pittdeptofmed.bsky.social 🎙️Frederik Filip Vinggaard Stæger @ffstaeger.bsky.social postdoc at Univ. of Copenhagen Info + Zoom link: varianteffect.org/seminar-series #Genetics #MedicalGenetics #FunctionalGenomics

POSTDOC ALERT: Applications now open for SeaBridge postdoc fellowship; opportunity to work on leading-edge biotech w/researchers at the Seattle Hub for Synthetic Biology. brotmanbaty.org/news/new-pos... @marionpepper.bsky.social @jshendure.bsky.social @coletrapnell.bsky.social

Zachary Amador, left, scientist w/Seattle Hub for Synthetic Biology, explains to artist Ranger Liu an experiment using DNA - they are collaborating togther in the Fred Hutch SxAffold "encounter" this week among artists & scientists. @fredhutch.bsky.social @calliechappell.bsky.social

Ranger Liu, artist & physicist working on a Ph.D. in Astronomy at UW, is working w/a SeattleHub researcher as part of SxAffold, the weeklong collaboration among scientists & artists at the Hutch. Photo by Connor O’Shaughnessy / Fred Hutch alleninstitute.org/division/sea... @fredhutch.bsky.social

TOMORROW - June 3 - at 9 AM - The Variant Effects Seminar Series will feature Ben Li (U of Michigan) & Vahid Aslanzadeh (U of Edinburgh) Details: www.varianteffect.org/seminar-seri... @varianteffect.bsky.social @uwmedicine.bsky.social

MS 2025 Update: @cwjpugh.bsky.social presents on 'Breaking the Scaling Barrier in Protein Variant Effect Prediction." @jonnyfrazer.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @varianteffect.bsky.social @fritzroth.bsky.social @muffley.bsky.social #VariantEffect25

@cwjpugh.bsky.social at #VariantEffect25

Update from MSS 2025 in Barcelona: Dave Adams of Wellcome-Sanger presents on how genetic variation impacts cancer disease risk. Photo: Jonathan Frazer @jonnyfrazer.bsky.social @varianteffect.bsky.social @davidjadams.bsky.social @lindorfflarsen.bsky.social @sangerinstitute.bsky.social

MSS 2025 is underway in Barcelona. Many thanks to Jonathan Frazier for posting updates regularly. Several BBI researchers are participating. @jonnyfrazer.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @muffley.bsky.social @shawnfayer.bsky.social #VariantEffect25

Let’s get this party started! Kicking off workshop 1 of #VariantEffect25 we have Albert Escobedo — From Fitness to Free Energy: Thermodynamic Modeling of Protein DMS Data for Accurate Genetic Prediction with MoCHI 🍡🧬

'Science can feel like magic. When you begin to understand how and why things work, it’s incredible.' Learn more about Katie Partington, an 'intellectually adventurous' promising young scientist in the lab of BBI's Dr. Doug Fowler. brotmanbaty.org/news/promisi... @dougfowler.bsky.social @hmc.edu

New paper by UW Medicine's Colin Pritchard clears up confusion on treating ‘passenger’ vs. ‘driver’ mutations in BRCA1 and 2 genes. Learn more. ascopubs.org/doi/pdf/10.1... @uwmedicine.bsky.social @ascocancer.bsky.social

Hi Jonathan, we at BBI are looking forward to your posts next week from MSS 2025 from Barcelona. Cheers! @jonnyfrazer.bsky.social @varianteffect.bsky.social @bennibolo.bsky.social #VariantEffects25

HUGE congrats Lara Muffley - honored w/ UW Distinguished Staff Award for Collaboration - advancing world-class research on genetic variants on behalf of BBI brotmanbaty.org/news/bbis-la... @varianteffect.bsky.social @leastarita.bsky.social @dougfowler.bsky.social @mehurles.bsky.social

Are you or someone you know affected by Hemophilia B? BBI's Drs. Jill Johnsen & Doug Fowler have advanced genetic understandinng of the blood disorder. Learn more. brotmanbaty.org/news/new-mut... @uwmedicine.bsky.social @dougfowler.bsky.social @hemophilia.bsky.social

AI & Precision Medicine: The Stuart and Molly Sloan Precision Oncology Institute at Fred Hutch Cancer Center is hosting a symposium on AI, on Tuesday, May 20. Learn how AI is shaping treatment, diagnosis & prevention strategies for cancer. @fredhutch.bsky.social www.fredhutch.org/en/events/st...

Next up for the Variant Effects Seminar Series: Tuesday, 6 May, 9am (Pacific) w/ Timothy Tan (U of Illinois) & Mustafa Tekpinar (Van Yüzüncü Yıl University). Details: www.varianteffect.org/seminar-seri... @uwgenome.bsky.social @varianteffect.bsky.social

Check out the newly refreshed Atlas of Variant Effects website: www.varianteffect.org/for A smoother & more intuitive experience. Kudos to the Wellcome Sanger Webdev team for their work @sangerinstitute.bsky.social

One never knows the power and persuasion of elementary school teachers. Jonas ("Gus") Gustafson's fifth grade instructor 'allowed me to establish a life-long knack and passion for STEM.’ @uwmedicine.bsky.social @danrdanny.bsky.social brotmanbaty.org/news/promisi...

New study in Genome Biology: Guidelines for releasing a variant effect predictor - 'enhance personalized medicine & genetic disease understanding, aligning w/calls for standardized, rigorous VEP practices in genomic medicine' genomebiology.biomedcentral.com/articles/10.... @broadinstitute.org

Looking Ahead: Mutational Scanning Symposium 2025, May 21-23, Barcelona, features Kresten Lindorff-Larsen addressing interface between variant effects & interpretation. Learn more: brotmanbaty.org/news/spotlig... @varianteffect.bsky.social @lindorfflarsen.bsky.social @bennibolo.bsky.social

'The lives of cells, recorded:' Nature perspective reflects foundational principles of Seattle Hub & 'further(s) our understanding of cell decisions over time, given their cellular ancestry & past cell trajectories.' @naturegenet.bsky.social @jshendure.bsky.social brotmanbaty.org/news/nature-...

TOMORROW - 9 am (Pacific) Variant Effects Seminar - Presentations by Joyce Kang (Harvard-MIT) and Yiyun Rao (Penn State) @broadinstitute.org @pennstateuniv.bsky.social @varianteffect.bsky.social Learn more: www.varianteffect.org/seminar-series

Mark your calendars now. The next variant effects seminar is Monday, 1 April, 9 am (Pacific), featuring Joyce Kang @harvard.edu @broadinstitute.org & Yiyun Rao @pennstateuniv.bsky.social. @varianteffect.bsky.social Learn more: www.varianteffect.org/seminar-series

How do get hired for a position that's "a perfect match" for your professional interests? Read - and be inspired by - Hina Iftikhar's story. @alleninstitute.bsky.social @genentech.bsky.social @chanzuckerberg.bsky.social @uwmedicine.bsky.social brotmanbaty.org/news/promisi...

New Paper Advances Understanding how Genetic Variations Drive Disease: ‘We were able to resolve genetic & molecular basis of (the patient’s) condition, providing both her family & care team w/ answers to support her moving forward.’ @naturegenet.bsky.social brotmanbaty.org/news/paper-a...

@uwmedicine.bsky.social "Huddle" underscores the importance of the new $10m grant to Seattle Hub huddle.uwmedicine.org/10m-awarded-... @alleninstitute.bsky.social @chanzuckerberg.bsky.social

How does a young person who loves both science and art decide on a career? Seattle Hub's Dr. Jonas Koeppel has a theory. @alleninstitute.bsky.social @jonaskoeppel.bsky.social @chanzuckerberg.bsky.social @sudpinglay.bsky.social brotmanbaty.org/news/promisi...

The Washington Research Foundation's $10M, 5-year grant will help move Seattle forward as the 'epicenter of synthetic biology.' @chanzuckerberg.bsky.social @alleninstitute.bsky.social brotmanbaty.org/news/washing...

NEXT TUESDAY: The March 4 session (10 am Pacific) of the Variant Effects Seminar Series will provide observations & insights from 3 engaging researchers: Shawn Fayer, Malvika Tejura & Zachary Walsh. Join: www.varianteffect.org/seminar-series @varianteffect.bsky.social

Key deadline is almost upon us for the 2025 Mutational Scanning Symposium in Barcelona. Three 3 more days. March 1st - for abstract submissions and early bird registration rates. events.ibecbarcelona.eu/mutational-s... @varianteffect.bsky.social #VariantEffect25

Updates on 2025 Mutational Scannning Symposium, May 21 to 23 in Barcelona: Insights and Observations from Wellcome Sanger's Dr. David Adams. @varianteffect.bsky.social @sangerinstitute.bsky.social brotmanbaty.org/news/q-and-a...

'Essential to the practice of precision medicine.' @uwmedicine.bsky.social piece examines BBI's global leadership in creating an atlas of genetic variant effects. @varianteffect.bsky.social @dougfowler.bsky.social @leastarita.bsky.social huddle.uwmedicine.org/mapping-gene...

@science.org profile of @sudpinglay.bsky.social reveals his passion for genetics was ignited by undergrad course that was a 'sweatship for DNA.' Congrats Sud! www.science.org/content/arti...

Be sure to join the next Variant Effects Seminar Series, February 4 at 9 am (Pacific), hosted by @varianteffect.bsky.social See: www.varianteffect.org/seminar-series

The Chan Zuckerberg Initiative is awarding BBI researchers $1.5 million over two years to “democratize” access to synthetic DNA. We are envisoning complementary technologies that address shortcomings of current systems for manufacturing DNA. brotmanbaty.org/news/chan-zu... @sudpinglay.bsky.social

REGISTER TODAY AND BOOK YOUR TRAVEL TO BARCELONA: Registration is now open for Eighth Annual Mutational Scanning Symposium, May 21st through 23rd in at the Barcelona Biomedical Research Park. Barcelona, Spain. brotmanbaty.org/news/registr... @varianteffect.bsky.social

IMPORTANT VARIANT ANALYSIS UPDATE: Members of the AVE Alliance, including BBI PIs Drs. Doug Fowler & Lea Starita, today published a curated community database w/7 million+ variant effects from multiplexed functional assays. genomebiology.biomedcentral.com/articles/10....

“It is the fundamental challenge of our time.” Learn more about that challenge in 'Understanding Genetic Variants in Context, published in eLife. Authors include several BBI faculty; Christine Queitsch, Ph.D., is a Corresponding Author. brotmanbaty.org/news/white-p...

Looking back: 2024 was a memorable year for BBI. Here are several exceptional events and peer-reviewed papers from 2024. brotmanbaty.org/news/bbi-yea...

@cziscience.bsky.social provides BBI $4.5 million to study genetic variants, including partnering w/patient organizations within CZI’s 'Rare As One' Project. brotmanbaty.org/news/chan-zu...

A dozen experts on computational biology to bioengineering to AI have been confirmed for the Eighth Annual Mutational Scanning Symposium, May 21st through 23rd in Barcelona, Spain. Registration opens January 20. Learn more: brotmanbaty.org/news/mss-202... @varianteffect.bsky.social

‘Bringing together the best of large-scale science and philanthropy:' SeaHub Celebrates First Anniversary – Learn more about this extraordinary research collaboration brotmanbaty.org/news/seahub-... @cziscience.bsky.social @alleninstitute.bsky.social @jshendure.bsky.social @uwseattle.bsky.social

"It's a fundamentally new paradigm for how we measure biology over time" BBI Scientific Director Dr. Jay Shendure quoted in @nytimes.com article. "‘DNA Typewriters’ Can Record a Cell’s History" www.nytimes.com/2024/11/25/s...

Greetings Bluesky colleagues: The Brotman Baty Institute is honored to join this growing platform. Here's a link to our website for more information about our work exploring opportunities at the interface of basic science and precision medicine: brotmanbaty.org Looking foward to connecting....