The new GRADE Guidance on using RCTs and NRSIs in evidence synthesis is out in JCE. Years of diagrams and domain debates distilled into a practical roadmap. If you work in guidelines or HTA, this one’s for you. #GRADE #EvidenceSynthesis #SystematicReview #HTA www.jclinepi.com/article/S089...

This infographic captures the full process in a single view.

#CochraneDaily Just published! Scoping review of 165 studies maps factors associated with citation rates and reasons for and extent of citation bias in the health literature www.jclinepi.com/article/S089... #Bias #Citation @jclinepi.bsky.social

Commentary: The many roles of decision thresholds for primary research, evidence synthesis and health decision-making - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Methodological Guidance for Individual Participant Data Meta-Analyses: A Systematic Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

The RoB-VE Project: Introduction to a methodological initiative to improve risk-of-bias assessment and reporting in #vaccine effectiveness research - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

GRADE guidance 44: Strategies to enhance the utilization of randomized and non-randomized studies in evidence syntheses of health interventions - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Hill’s Considerations Are Not Causal Criteria - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Discrimination, calibration, and variable importance in statistical and machine learning models for predicting overall survival in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

The loss of efficacy of fluoxetine in pediatric depression: explanations, lack of acknowledgment, and implications for other treatments - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Approaches for reporting and interpreting statistically nonsignificant findings in evidence syntheses: A systematic review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Including nonrandomized evidence in living systematic reviews: lessons learned from the COVID-NMA initiative - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A Scoping Review of Critical Appraisal Tools and User Guides for Systematic Reviews with Network Meta-Analysis: Methodological Gaps and Directions for Tool Development - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Use of structured tools by peer reviewers of systematic reviews: a cross-sectional study reveals high familiarity with PRISMA but limited use of other tools - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 4: Interest-holder engagement - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Methods Handbooks Paper 9: Cooperative Approaches - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 6: Adaptation of Practice Guidelines - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 7: Updating Practice Guidelines - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 1: Introduction - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 5: Conflict of Interest and Funding - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 10: Developing Recommendations About Diagnostic Tests and Strategies - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

User experiences of qualitative evidence in the GRADE Evidence-to-Decision framework – Findings from Malawi, Nigeria and South Africa. - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

(1/2) Please share: Save the date for the next KT Canada Summer Institute! The 2026 Summer Institute will be in Ottawa, Ontario from June 8-10. This year, there will be an option to stay another day and participate in the inaugural Ottawa Evidence to Action Showcase event! #ImpSci

Co-designed with our Knowledge Translation Committee, this resource aims to: - Share research activities and findings with various audiences - Increase awareness and promote meaningful change in research and practice #KnowledgeMobilization

Conçue en collaboration avec notre comité d’application des connaissances, cette ressource vise à : - Présenter les activités et les résultats de recherche avec divers publics - Sensibiliser le public et promouvoir les changements positifs dans la recherche et la pratique

DEADLINE EXTENDED TO NOVEMBER 27, 2025 - There’s still time to register for the Digital Health Literacy for Older Adults (DHLOA) in-person knowledge mobilization event! Sign up as a Person with Lived Experience: tinyurl.com/bp5bn6wr Sign up as a General Attendee: tinyurl.com/48x8x5e2 /1

Register by Nov 27, 2025 — space is limited! Honoraria available for older adults with lived experience (first come, first served). #DigitalHealth #HealthLiteracy #PatientEngagement #OlderAdults @andreatricco.bsky.social @ktcanada.bsky.social

Ces ressources fournissent des informations sur l’expérience des patients partenaires, des membres du public et des chercheurs coresponsables dans la conduite de projets axés sur le patient. #CommunautésDePratique #EngagementDesPatients #RechercheAxéeSurLePatient #MobilisationDesConnaissances /2

Check out this recent op-ed from KTP Director Dr Sharon Straus & Dr Stephen Toope, where they discuss whether the Government of Canada’s latest budget meets the moment, on behalf of The Royal Society of Canada. bit.ly/4r8KFhd #Innovation @andreatricco.bsky.social @sporalliance.bsky.social

The effects of recreational cannabis use on glycemic outcomes and self-management behaviours in people with type 1 and type 2 diabetes: a rapid review - systematicreviewsjournal.biomedcentral.com/articles/10....

Comparative Efficacy and Safety of Ultra-Long-Acting, Long-Acting, Intermediate-Acting, and Biosimilar Insulins for Type 1 Diabetes Mellitus: a Systematic Review and Network Meta-Analysis - link.springer.com/article/10.1...

Comparative efficacy and complications of long-acting and intermediate-acting insulin regimens for adults with type 1 diabetes: an individual patient data network meta-analysis - bmjopen.bmj.com/content/12/1...

It's #DiabetesAwarenessMonth! In this study, our Knowledge Synthesis Team compared the cost-effectiveness of different types of insulin. See what they found! pubmed.ncbi.nlm.nih.gov/35341688/ Check out more of our work on diabetes in the comments. @andreatricco.bsky.social

The @jclinepi.bsky.social November issue is online! www.jclinepi.com/current

Editors’ choice - November 2025: Methods for Living Guidelines Series - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Key Concepts series: Overview of evidence synthesis types and modes - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Key concepts: FAIRification of biomedical research data - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Potential Waste in Evidence Synthesis for Health Screening: A Scoping Review and Call for Action - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 11: Quality Assurance and Improvement in Guideline Development - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Guideline Organizations’ Guidance Documents Paper 8: Considering equity - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Developing a framework for assessing the applicability of the target condition in diagnostic research - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Key concepts series: Estimands: what they are and why we should use them - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Identifying ethical issues in stepped-wedge cluster randomized trials to inform the Ottawa Statement update: a systematic review of trials published 2016-2022 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Scalable Medication Extraction and Discontinuation Identification from Electronic Health Records Using Large Language Models - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Dysinclusion: Naming and defining the inequitable absence of marginalized populations in health research - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Excellent and highly readable explanation of ESTIMANDS, and how thinking carefully about them clarifies planning, and interpretation of results from, any clinical trial. www.jclinepi.com/article/S089... And full text is freely available.

(1/3) You’re Invited - Join us for the Digital Health Literacy for Older Adults In-Person Knowledge Mobilization Event! Sign up as a Person with Lived Experience: tinyurl.com/bp5bn6wr Sign up as a General Attendee: tinyurl.com/48x8x5e2 @andreatricco.bsky.social @sporalliance.bsky.social

You’re Invited - Join us for the Digital Health Literacy for Older Adults (DHLOA) In-Person Knowledge Mobilization Event! Sign up as a Person with Lived Experience: tinyurl.com/bp5bn6wr Sign up as a General Attendee: tinyurl.com/48x8x5e2 /1

Register by Nov 25, 2025 — space is limited! Honoraria available for older adults with lived experience (first come, first served). Access the flyer for more info: shorturl.at/cXRzg #DigitalHealth #HealthLiteracy #PatientEngagement #OlderAdults @andreatricco.bsky.social @ktcanada.bsky.social

Editors' choice: The challenges and opportunities of artificial intelligence and their impact on the journal - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...